Rena Ruiyu Xian, M.D., M.S.

Headshot of Rena Ruiyu Xian
  • Associate Professor of Pathology

Languages: English, Mandarin


Dr. Rena Xian is an associate professor of Pathology and Oncology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include diagnostic hematopathology and molecular pathology. Dr. Xian has developed numerous molecular assays and is an expert in clinical next-generation sequencing. 

Her research focuses on genetic alterations of hematologic malignancies, particularly B-cell neoplasms, non-invasive disease biomarkers, and viral-associated lymphomas. Dr. Xian is interested in the application of large-scale genomics and novel molecular techniques to cancer diagnosis, prognosis, and therapeutics. 

Dr. Xian is also passionate about medical education, and the training of genetically-informed physicians. She is active in several professional societies, including the Association for Molecular Pathology, the College of American Pathologists, and the American Society of Hematology. 

Prior to joining Johns Hopkins, Dr. Xian was an assistant professor of Pathology and Lab Medicine at University of California, Los Angeles. more


  • Associate Professor of Pathology
  • Associate Professor of Oncology

Departments / Divisions

Centers & Institutes



  • MD; Northwestern University Feinberg School of Medicine (2009)


  • Anatomic and Clinical Pathology; Hospital of the University of Pennsylvania (2013)


  • Molecular Genetic Pathology; David Geffen School of Medicine at UCLA (2015)
  • Hematopathology; Johns Hopkins University School of Medicine (2014)

Board Certifications

  • American Board of Pathology (Anatomic & Clinical Pathology) (2013)
  • American Board of Pathology (Hematology) (2014)
  • American Board of Pathology (Molecular Genetic Pathology) (2015)

Research & Publications

Academic Affiliations & Courses

Graduate Program Affiliation

Program Director, Molecular Genetic Pathology Fellowship

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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